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Chinese Journal of Mycology    2015, 10 (4): 234-235.   Abstract （1171）      PDF （802KB）（1401）       Knowledge map    Save Reference | Related Articles | Metrics

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Clinical Application of Terbinafine：Expert consensus Expert group of consensus on the clinical application of Terbinafine Chinese Journal of Mycology    2020, 15 (5): 257-261.   Abstract （298）      PDF （768KB）（631）       Knowledge map    Save Reference | Related Articles | Metrics

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Guidelinesforthe diagnosis andtreatment oftinea corporis andtinea crurisin China The Working Group on Guidelinesforthe Diagnosis and Treatment of Tinea corporis and Tinea Crurisin China Chinese Journal of Mycology    2023, 18 (3): 193-197.   Abstract （273）      PDF （740KB）（470）       Knowledge map    Save Reference | Related Articles | Metrics

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Chinese Journal of Mycology    2017, 12 (6): 321-324.   Abstract （381）      PDF （814KB）（1967）       Knowledge map    Save Reference | Related Articles | Metrics

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Chinese Journal of Mycology    2021, 16 (1): 1-5.   Abstract （345）      PDF （887KB）（635）       Knowledge map    Save Reference | Related Articles | Metrics

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Epidemiology of invasive aspergillosis in China XU Yuan, CHEN Min, LIAO Wan-qing Chinese Journal of Mycology    2018, 13 (1): 57-60.   Abstract （982）      PDF （781KB）（2390）       Knowledge map    Save Invasive aspergillosis (IA) is a serious opportunistic infection that mainly been found in individuals with a compromised immune system. As Aspergillus species worldwide and the increasing number of immunocompromised hosts, IA brings a heavy burden to our country. In addition, early diagnosis is difficult and effective treatments are lacking, which leaded to the high mortality of IA (39%~100%). Currently, further nationwide epidemiological research of IA is needed in China. Reference | Related Articles | Metrics

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Chinese Journal of Mycology    2020, 15 (6): 325-330.   Abstract （1240）      PDF （899KB）（905）       Knowledge map    Save Reference | Related Articles | Metrics

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Clinical application of terbinafine in the treatment of subcutaneous and deep mycosis ZHU Hong-mei, WEN Hai Chinese Journal of Mycology    2020, 15 (6): 374-377.   Abstract （670）      PDF （883KB）（183）       Knowledge map    Save Terbinafine is an active allylamine antifungal agent with a mechanism of inhibiting squalene epoxidase in the fungal cell membrane. Its spectrum of in vitro fungicidal activity includes a broad range of dermatophyte, filamentous, dimorphic fungi, and some yeast species. Terbinafine had been widely used as the first-line treatment for superficial dermatophyte infection. In nearly two decades, terbinafine also had been proved to be highly effective and safe for a variety of subcutaneous and deep fungal infections, either in monotherapy or in combination therapy. Reference | Related Articles | Metrics

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Special stains in fungal histopathology MA Tian, SONG Yue-xing, ZOU Xian-biao Chinese Journal of Mycology    2011, 6 (6): 367-369.   Abstract （2057）      PDF （342KB）（3558）       Knowledge map    Save Histological evaluation is quick and easy for pathogen identification and diagnosis in fungal infections.Some common special stains and application will be discussed in this paper. Reference | Related Articles | Metrics Cited: Baidu(5)

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A rapid and efficient extraction method of fungus DNA for PCR CHAI Hai-yun, ZHANG Lei, YUAN Mu-ge, ZHU Qing-yi Chinese Journal of Mycology    2017, 12 (6): 359-361,367.   Abstract （701）      PDF （1508KB）（1399）       Knowledge map    Save Objective To explore a new convenient and efficient fungi DNA extraction method,which could be used in many kinds of fungi.Methods We associated enzymic digestion with Chelex-100 to make up a new reagent for fungi DNA extraction.Results During the experiment,34 strains were tested.The DNAs of 32 strains could be obtained by our reagent,while only 27 strains' DNAs could be extracted by Takara lysis buffer.For the strains we did not successfuly obtain the DNA by the above methods,we grinded the fungi by liquid nitrogen.After that,our reagent obtained their DNA by,and only one by Takara lysis buffer.Conclusion The DNA extraction efficiency of our reagent is much better than that of Takara lysis buffer.It can be used in many kinds of fungi.For some fungi,we should firstly grind it before DNA extraction. Reference | Related Articles | Metrics

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Chinese Journal of Mycology    2019, 14 (3): 183-188,192.   Abstract （476）      PDF （945KB）（883）       Knowledge map    Save Reference | Related Articles | Metrics

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Chinese Journal of Mycology    2019, 14 (3): 180-182.   Abstract （403）      PDF （774KB）（958）       Knowledge map    Save Reference | Related Articles | Metrics

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Progess of topical antifungal agents for the treatment of onychomycosis WANG Ruo-jun, LI Ruo-yu, WANG Ai-ping Chinese Journal of Mycology    2018, 13 (2): 114-119.   Abstract （592）      PDF （854KB）（1136）       Knowledge map    Save In this article, we reviewed topical antifungal agents for the treatment of onychomycosis at present, including the widely used agents, 8% ciclopirox nail lacquer and 5% amorolfine nail lacquer, and the agents recently approved by the FDA, 10% efinaconazole and 5% tavaborole solution, as well as luliconazole and tazarotene which being still in studies. The use of new formulations of topical antifungal drugs were also included in this review. Reference | Related Articles | Metrics

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Chinese Journal of Mycology    2022, 17 (6): 513-516.   Abstract （101）      PDF （793KB）（97）       Knowledge map    Save Reference | Related Articles | Metrics

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Chinese Journal of Mycology    2023, 18 (3): 265-269.   Abstract （67）      PDF （884KB）（222）       Knowledge map    Save Reference | Related Articles | Metrics

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Analysis of the growth characteristics of Aspergillus fumigatus in different temperature and nutrient media ZHANG Jin-qing, LIU Wei, TAN Jing-wen, WAN Zhe, LI Ruo-yu Chinese Journal of Mycology    2013, 8 (1): 6-9.   Abstract （1490）      PDF （949KB）（1345）       Knowledge map    Save Objective To determine the growth characteristics of Aspergillus fumigatus in different nutrient media and temperature.Methods Growth curves were used to determine the optimum medium, optimum and maximum growth temperatures for two strains of Aspergillus fumigatus:colony counts were used to determine the fatal temperatures for them.Results Three different nutrient media, yeast extract medium (YG), minimal medium (MM) and yeast nitrogen base (YNB), were tested. YG medium was the optimum medium for measuring the growth curves of Aspergillus fumigatus; In YG medium, the optimum growth temperature for Aspergillus fumigatus was 37℃, and the maximum growth temperature was 52℃. The slower growth rates of strains were observed with gradually elevated temperature. Unexpectedly, the responses of these two strains to high temperature were different:one strain's growth became slower markedly at 48℃ than at 37℃ during log phase, while the other one grew at 48℃ as well as at 37℃ during log phase. The strains of Aspergillus fumigatus were dead when exposed to 65℃ lasting more than 180 min or 70℃ lasting more than 120 min.Conclusions The optimum and the maximum growth temperature for Aspergillus fumigatus were 37℃ and 52℃, respectively.The fatal condition for Aspergillus fumigatus was 65℃ lasting more than 180 min or 70℃ lasting more than 120 min. Reference | Related Articles | Metrics

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Chinese Journal of Mycology    2022, 17 (6): 522-528.   Abstract （75）      PDF （889KB）（143）       Knowledge map    Save Reference | Related Articles | Metrics

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Chinese Journal of Mycology    2010, 5 (2): 65-68,86.   Abstract （1262）      PDF （799KB）（1571）       Knowledge map    Save Reference | Related Articles | Metrics

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Evaluation of ITS, BenA and CaM in identification of clinical Aspergillus LI Ying, XU Ying-chun Chinese Journal of Mycology    2017, 12 (2): 74-77.   Abstract （875）      PDF （786KB）（1847）       Knowledge map    Save Objective To evaluate the internal transcribed spacer (ITS), β-tubulin gene (BenA) and calmodulin gene (CaM) sequence analysis in identification of clinical Aspergillus.Methods All 169 strains of Aspergillus collected from clinical patients were analyzed by ITS, BenA, CaM sequencing to obtain the species information with reference to the Genbank database.Results The tested strains were identified to species level with identification rates of 52.7% (89/169), 66.3% (112/169), 97.6% (165/169) and to genus level of 47.3% (80/169), 33.7% (57/169), 2.4% (4/169) by ITS, BenA and CaM, respectively.None of the three sequence markers failed in identification of Aspergillus.Conclusion ITS, BenA and CaM can be used to identify clinical Aspergillus.Among them, CaM is the most efficient molecular marker for Aspergillus identification. Reference | Related Articles | Metrics

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Correlation analysis of TFP1 gene and calcineurin pathway of Candida albicans MENG Lingning, LIU Jinyan, XIANG Mingjie, SHEN Han Chinese Journal of Mycology    2021, 16 (4): 217-221.   Abstract （167）      PDF （1084KB）（153）       Knowledge map    Save Objective To construct the TFP1 gene knockout strains of Candida albicans and analyze the relationship between TFP1 gene and genes related to calcineurin pathway. Methods The upstream and downstream flanking sequences of TFP1 gene and the screened markers were connected to form the gene knockout fragments through fusion PCR, and then transferred into Candida albicans SN152 by lithium acetate transfection method. TFP1+/- strains were then screened out. The second allele was knocked out by the same method. Quantitative real-time PCR was used to detect the expression levels of RTA2 and CRZ1 genes of TFP1-/- strain, TFP1+/- strain and SN152 strain. Results The Candida albicans SN152 TFP1-/- double allelic deletion strains were successfully constructed, and the expression levels of RTA2 and CRZ1 genes in the SN152 TFP1-/- strains were both decreased. Conclusion TFP1 gene of Candida albicans is related to calcineurin pathway. Reference | Related Articles | Metrics

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Chinese Journal of Mycology    2022, 17 (1): 1-7.   Abstract （84）      PDF （817KB）（364）       Knowledge map    Save Reference | Related Articles | Metrics

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Chinese Journal of Mycology    2022, 17 (1): 74-77.   Abstract （0）      PDF （811KB）（272）       Knowledge map    Save Reference | Related Articles | Metrics

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Chinese Journal of Mycology    2022, 17 (4): 349-352.   Abstract （46）      PDF （814KB）（189）       Knowledge map    Save Reference | Related Articles | Metrics

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Chinese Journal of Mycology    2015, 10 (3): 182-184,189.   Abstract （877）      PDF （1349KB）（2279）       Knowledge map    Save Reference | Related Articles | Metrics

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Chinese Journal of Mycology    2012, (2): 111-115.   Abstract （2029）      PDF （842KB）（1004）       Knowledge map    Save Reference | Related Articles | Metrics

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Chinese Journal of Mycology    2016, 11 (1): 62-64.   Abstract （857）      PDF （798KB）（1562）       Knowledge map    Save Reference | Related Articles | Metrics

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Chinese Journal of Mycology    2015, 10 (2): 118-125.   Abstract （956）      PDF （907KB）（1198）       Knowledge map    Save Reference | Related Articles | Metrics

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Chinese Journal of Mycology    2022, 17 (2): 89-93.   Abstract （102）      PDF （1299KB）（222）       Knowledge map    Save Reference | Related Articles | Metrics

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Chinese Journal of Mycology    2023, 18 (3): 270-272,281.   Abstract （45）      PDF （905KB）（85）       Knowledge map    Save Reference | Related Articles | Metrics

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Chinese Journal of Mycology    2023, 18 (1): 58-64.   Abstract （85）      PDF （1484KB）（183）       Knowledge map    Save Reference | Related Articles | Metrics

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Chinese Journal of Mycology    2011, 6 (6): 381-384.   Abstract （1321）      PDF （297KB）（1861）       Knowledge map    Save Reference | Related Articles | Metrics

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Chinese Journal of Mycology    2015, 10 (5): 317-320.   Abstract （790）      PDF （807KB）（2669）       Knowledge map    Save Reference | Related Articles | Metrics

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Chinese Journal of Mycology    2017, 12 (1): 52-57.   Abstract （715）      PDF       Knowledge map    Save Reference | Related Articles | Metrics

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Chinese Journal of Mycology    2019, 14 (3): 189-192.   Abstract （310）      PDF （871KB）（796）       Knowledge map    Save Reference | Related Articles | Metrics

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Chinese Journal of Mycology    2022, 17 (4): 319-323.   Abstract （50）      PDF （847KB）（200）       Knowledge map    Save Reference | Related Articles | Metrics

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Meta-analysis of trimethoprim-sulfamethoxazole combined with caspofungin in the treatment of Pneumocystis jirovecii pneumonia DUNA Yan, XU Yuan, YANG Changqing, ZHANG Jinping Chinese Journal of Mycology    2023, 18 (1): 1-7.   Abstract （167）      PDF （2630KB）（160）       Knowledge map    Save Objective To systematically evaluate the efficacy and safety of trimethoprim-sulfamethoxazole (TMP/SMZ) combined with caspofungin in the treatment of Pneumocystis jirovecii pneumonia (PJP). Methods PubMed, Embase, Cochrane library, CBM, CNKI, Wanfang, VIP were searched for clinical randomized controlled trials of TMP/SMZ combined with caspofungin in the treatment of PJP, and Meta-analysis was performed. The outcome indicators were total effective rate, incidence of adverse reactions Statistical analysis was performed using RevMan 5.4 software. Results A total of 20 studies were included, involving 1 802 PJP patients. Meta-analysis results showed that compared with TMP/SMZ monotherapy, the effective rate of TMP/SMZ combined with caspofungin in the treatment of PJP was significantly improved, [RR =1.29, 95% CI (1.22,1.37),P< 0.00001], and no Increase the incidence of adverse drug reactions [RR =0.91,95% CI(0.79, 1.05),P=0.21>0.05]. Conclusion The effect of TMP/SMZ combined with caspofungin in the treatment of PJP is better than that of TMP/SMZ monotherapy, without increasing adverse drug reactions, and it is recommended for clinical use. Reference | Related Articles | Metrics

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Chinese Journal of Mycology    2011, 6 (1): 51-56.   Abstract （1993）      PDF （914KB）（971）       Knowledge map    Save Reference | Related Articles | Metrics

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Glucocorticoids and invasive fungal infections:a review HAO Fei, WANG Li, ZHOU Cun-jian Chinese Journal of Mycology    2012, 7 (6): 367-371.   Abstract （1624）      PDF （796KB）（1744）       Knowledge map    Save It is well-known that hyperglucocorticoids play an important role in inducing the fungal infection,especially opportunistic fungal infection,which is attributed to the complex dysregulation of immunity caused by glucocorticoids.The patients, both those with endogenous Cushing's syndrome and, those receiving exogenous glucocorticoid therapy, are especially at risk of invasive fungal infections. A better knowledge of the interplay between glucocorticoid-induced immunosuppression and invasive fungal infections should assist in earlier recognition and establishment of specific prevention and treatment strategies in order to improve outcomes of such infections. Reference | Related Articles | Metrics Cited: Baidu(26)

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Pattern regcognition receptors and signaling pathways in Cryptococcus neoformans LI Ying-fang, PAN Wei-hua Chinese Journal of Mycology    2016, 11 (1): 58-61.   Abstract （1072）      PDF （839KB）（1183）       Knowledge map    Save Pattern recognition receptors(PRRs) presented on the surface of host innate immune cells recognize the pathogen-associated molecular patterns(PAMPs) of Cryptococcus neoformans after the invasion,which will trigger downstream sinaling pathways and activate nuclear factor-kappa B(NF-κB) in immune cells,ultimately initiating innate and adaptive immunity,inducing the release of correlative inflammatory factors,activating adaptive immune cells such as Th1,Th2,Th17 cells,recruiting macrophage to eliminate Cryptococcus neoformans.Deep insights into PRRs and downstream pathways will contribute to obtain an overall understanding of immune adjustment and provide superior clinical therapys. Reference | Related Articles | Metrics

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Chinese Journal of Mycology    2017, 12 (6): 375-377.   Abstract （286）      PDF （803KB）（734）       Knowledge map    Save Reference | Related Articles | Metrics