Characteristics and risk factors of fungal infection after urinary surgery

Abstract

Abstract: Objective To investigate the characteristics and risk factors of postoperative fungal infection in urinary system. Methods The clinical data of 762 patients with urinary system diseases who underwent urological surgery in our hospital from June 2017 to may 2021 were retrospectively analyzed. According to whether they had urinary system and blood fungal infection after operation, they were divided into infection group (n=75) and non infection group (n=687). The clinical data of the two groups were compared, and univariate analysis and logistic regression analysis were performed. Results 75 of the 762 patients had postoperative fungal infection, the incidence was 9.84%. The main disease type was urinary calculi, the main pathogen was Candida, and the main indwelling catheters were DJ tube and catheter; Among 75 cases of fungal infection after urinary system operation, 69 cases were asymptomatic, 5 cases had frequent urination, urgency and pain, and 1 case had chills, fever and low back pain. The results of univariate analysis showed that the proportion of age >65 years, open operation, operation time ≥ 30 min, drainage tube retention time >7 d, antibacterial drug use time ≥ 3 d in the infection group was higher than that in the non infection group (P<0.05), and the blood glucose level and CRP level in the infection group were higher than those in the non infection group (P<0.05); Logistic multivariate analysis showed that age (OR=1.604), operation method (OR=1.139), catheter retention time (OR=2.537), blood glucose level (OR=2.753), antibacterial drug use time (OR=2.508) and CRP (OR=3.057) were independent risk factors for fungal infection after urinary surgery (P<0.05). Conclusion The common pathogen of postoperative fungal infection in urinary system was Candida and most of them had no clinical symptoms. The common disease was urinary calculi. The common catheters indwelling were DJ tube and catheter. Age >65 years old, open surgery, catheter retention time >7 d, elevated blood glucose level, more than 3 d use of antibiotics, and elevated CRP were independent risk factors for postoperative urinary fungal infection, which need targeted intervention.

Key words: urinary system, mycotic infection, risk factors

CLC Number:

R519

YAN Qiu, LIU Hong. Characteristics and risk factors of fungal infection after urinary surgery[J]. Chinese Journal of Mycology, 2023, 18(1): 8-11,18.

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