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Chinese Journal of Mycology 2022, Vol. 17  Issue (3): 227-230.

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Effect of terbinafine hydrochloride cream combined with 3% boric acid alcohol ear drops on fungal otitis externa

DU Yucong, LIU Huanhai   

  1. Department of Otorhinolaryngology Head and Neck Surgery, Changzheng Hospital, Naval Medical University, Shanghai 200003, China
  • Received:2021-09-15 Online:2022-06-28 Published:2022-07-02

Abstract: Objective To explore the clinical efficacy of THC combined with 3% baa ear drops in the treatment of mycosis. Methods A total of 144 patients with external auditory canal mycosis treated in our hospital were enrolled. The patients were randomly divided into group A and group B. Group A was treated with 3% BAA and THC, and group B was treated with BAA alone. The therapeutic effects and fungal culture results of the two groups were compared and analyzed. Results The cure rate and clinical efficacy score of group A were significantly higher than those of group B (P<0.05); The improvement of pruritus, otorrhea and tinnitus in group A was more obvious than that in group B (P<0.05); Aspergillus and Candida accounted for 57.7% and 22.5% in the positive fungal culture, and they were highly sensitive to terbinafine. Conclusion THC combined with 3% baa ear drops is an effective method for the treatment of fungal otitis externa.

Key words: terbinafine, boric acid, fungal otitis externa

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