Analysis of fungal pathogens in 625 cases of tinea capitis in Hubei province and surrounding areas

Abstract

Abstract:

Objective To analyze the pathogens and clinical characteristics of tinea capitis cases in Hubei province and surrounding areas during the period 2011 to 2018. Methods The basic information of patients diagnosed as tinea capitis in the mycology laboratory,department of Wuhan first hospital from 2011 to 2018 were retrospectively analyzed. Results A total of 625 patients were diagnosed tinea capitis, include 252 males and 373 females, with onset ages ranging from 1 month to 84 years old. Positive culture: 507 (81.24%) cases, negative culture: 118 (18.76%) cases. Pathogenic fungus was given priority to with Trichophyton violaceum (49.90%), followed by Microsporum canis, Trichophyton mentagrophytes, Trichophyton tonsurans, Trichophyton rubrum, Microsporum gypseum, Microsporum ferrugineum, Trichophyton schoenleinii. Among the culture-positive patients, 80 (15.78%) were adults. The highest prevalence was seen in the 0 to 12 years old group (82.65%). The priority of clinical manifestation was black-dot ringworm (57.99%), tinea alba, kerion, tinea favosa were rare. Conclusion The tinea capitis patients in Hubei province and surrounding areas was concentrated in 0-12 years old. The most common type was black-dot ringworm, mainly caused by Trichophyton violaceum.

Key words: tinea capitis, pathogenic fungi, epidemiology, Trichophyton violaceum

CLC Number:

R756.1

FANG Mei-zhen, LIU Zhong, JIANG Ping, YANG Jing, DONG Bi-lin, ZENG Zhi-liang, CHEN Zun-yi, TONG Zhong-sheng. Analysis of fungal pathogens in 625 cases of tinea capitis in Hubei province and surrounding areas[J]. Chinese Journal of Mycology, 2020, 15(5): 274-277.

References 13

[1]	Chokoeva AA,Zisova L,Sotiriou E,et al.Tinea capitis:a retrospective epidemiological comparative study[J].Wien Med Wochenschr,2017,167(3-4):51-57.
[2]	del Boz-González J.Tinea capitis:trends in Spain[J].Actas dermo-sifiliográficas,2012,103(4):288-293.
[3]	中国头癣诊疗指南工作组.中国头癣诊断和治疗指南(2018修订版)[J].中国真菌学杂志,2019,14(1):4-6.
[4]	张小鸣,于英瑶,葛新红,等.宁夏203例儿童头癣病原菌分析[J].宁夏医科大学学报,2012,34(01):66-68.
[5]	Zhan P, Geng C, Li Z, et al. Evolution of tinea capitis in the Nanchang area, Southern China:a 50-year survey (1965-2014)[J]. Mycoses, 2015, 58(5):261-266.
[6]	郑文爱,唐小正.海南地区35例头癣临床和病原菌分析[J].中国麻风皮肤病杂志,2018,34(6):357-359.
[7]	徐续玲,曾志良,周绍稳,等.武汉及周边地区456例头癣患者分类病原菌检测分析[J].临床皮肤科杂志,2006,35(6):380-381.
[8]	喻惠元,陈尊义,董碧麟,等.武汉及其周边地区2011-2015年头癣类型及病原菌分析[J].中国皮肤性病学杂志,2017,31(3):324-326.
[9]	毛叶红,何蒙文,郑岳臣,等.1960-2015年湖北及周边地区头癣病原菌变化情况分析[J].中国真菌学杂志,2017,12(2):98-101,105.
[10]	许斌,胡志敏,段逸群.老年黑点癣误诊为脂溢性皮炎1例报道[J].华中医学杂志,2007,31(5):376.
[11]	李发增,冉玉平,代亚玲,等.表现为脂溢性皮炎样的儿童头癣1例[J].中国真菌学杂志,2009,4(3):160-161.
[12]	Park SK,Park SW,Yun SK,et al.Tinea capitis in adults:A 18-year retrospective, single-centre study in Korea[J].Mycoses,2019,62(7):609-616.
[13]	Cremer G, Bournerias I, Vandemeleubroucke E,et al. Tinea capitis in adults:misdiagnosis or reappearance[J]? Dermatology,1997,194(1):8-11.

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