Retrospective analysis of chromoblastomycosis in mainland China: a review of 52 cases

Abstract

Abstract:

Objective To summarize and explore the epidemiology, diagnosis and treatment of chromoblastomycosis in mainland China. Methods The relevant literatures about chromoblastomycosis in mainland China were collected from the electrical databases since 1994, such as Chongqing Weipu, China knowledge Network, Wanfang Database and PubMed database. Results A total of 29 literatures and 52 cases were searched. The average age of onset was 53.9 years old, and the ratio of male to female was 5.5:1; the disease was common in farmers and workers, with a history of trauma in the distal part of the extremities; most of the early onset is mainly papules, followed by plaques, nodules and ulcers; mycological examination strains is mainly Fonsecaea pedrosoi, and the most common treatments are itraconazole and terbinafine. The prognosis is good. Conclusions Chromomycosis is a chronic and refractory subcutaneous granulomatous disease with various clinical manifestations. It can cause teratogenic disability and even cancer in the late stage. Early diagnosis and treatment of the disease is very important.

Key words: chromoblastomycosis, fungus, epidemiology

CLC Number:

R519.2

SUN Qi-lin, YU Min, CHEN Jun, LIU Yang, LIAO Wan-qing, XU Hui, YANG Ya-li. Retrospective analysis of chromoblastomycosis in mainland China: a review of 52 cases[J]. Chinese Journal of Mycology, 2020, 15(2): 101-105.

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