Abstract:

Objective To observe the therapeutic effect and safety of luliconazole cream combined willow acid solution sprays in malassezia folliculitis. Methods 102 patients with malassezia folliculitis were randomly divided into three groups. The patients in the experimental group were treated with luliconazole cream combined willow acid solution sprays, once alternately in turn each morning and evening for 4 weeks; the patients in the first control group were treated with luliconazole cream, once a day for 4 weeks; and the patients in the second control group were treated with willow acid solution sprays, twice a day for 4 weeks. The therapeutic effect and the fungus clearance rate were observed after the treatment for 4 weeks. Results The therapeutic rate of the experimental group was 88.24%,which was higher than that of the first control group, there was a significant difference between the two groups(P=0.03).There was no significant difference between the experimental group and the second control group(P=0.08).The fungus clearance rate in the experimental group(91.18%) was higher than the first control group(75%) and the second control group(80.65%),there was no significant difference among the three groups(P=0.21). Conclusion Luliconazole cream combined willow acid solution sprays is effective and safe in the treatment of malassezia folliculitis.

Key words: luliconazole cream, willow acid solution sprays, Malassezia folliculitis, efficacy