Retrospective analysis of 1935 clinical deep Aspergillus isolates

Abstract

Abstract:

Objective To investigate the constitutionand the clinical distribution of the Aspergillus species in our hospital. To study the underlying diseases of aspergillosis patients and guide the prevention and treatment of aspergillosis. Methods Clinical information of the Aspergillus species strains isolated in the mycology laboratoryof hospital from January 2012 to December 2018 was collected for statistical analysis. Results In total 1935 Aspergillus isolates from culture-positive specimen, there were 159 Aspergillus niger, 77 Aspergillus flavus, 863 Aspergillus fumigatus and 836 undefined Aspergillus species. Aspergillus fumigates strains were mainly isolated from respiratory specimens. Hospitalized patients with A. fumigatus specimens were mainly distributed in the departments of infectious diseases, respiratory diseases, geriatrics, intensive care unit (ICU), antibiotics, senior wards and neurosurgery. The main underlying diseases of patients with clinical diagnosis of A. fumigatus infection were infectious disease, other chronic lung disease, tumor, rheumatic disease, diabetes and so on. Conclusion A. fumigatus was the most common Aspergillus species in the clinic in our hospital and mainly caused lung infection. Patients in departments mentioned above with related underlying diseases should be alert to Aspergillus infection.

Key words: Aspergillus, Aspergillus fumigatus, epidemiology

CLC Number:

R519.8

SU Hui-lin, CHEN Zong-qian, ZHU Jun-hao, LI Li, ZHANG Qiang-qiang, XU Jin-hua, ZHU Min. Retrospective analysis of 1935 clinical deep Aspergillus isolates[J]. Chinese Journal of Mycology, 2019, 14(4): 217-221.

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