Clinical observation of long-pulsed 1064nm laser combined with ketoconazole ointment in the treatment of onychomycosis

Abstract

Abstract:

Objective To observe the clinical efficacy of long-pulsed 1064nm laser combined with ketoconazole ointment in the treatment of onychomycosis. Methods Seventy-three outpatients with onychomycosis were randomly divided into two groups:the combined group (37 cases, 75 affected nails) was treated with 1064nm long-pulsed laser combined with ketoconazole ointment encapsulation of affected nails; the control group (36 cases, 87 affected nails) was treated with laser only. The patients were treated once a week for 8 weeks and followed up after 6 months. Results The total clinical effective rate (74.67%) of the combined group was higher than that of the control group (63.22%).The clinical effective rate of the three clinical types in the combined group was also higher than that of the control group, especially the proximal subungual type (PSO), but there was no significant difference in statistics. The clinical effective rate of onychomycosis with a score of 9 ≤ SCIO ≤ 15 in the combined group was higher than that of the control group. Conclusion The clinical efficacy of long-pulsed 1064nm laser combined with ketoconazole ointment in the treatment of onychomycosis patients with SCIO value of 9 ≤ SCIO ≤ 15 was significantly higher than that of laser only.

Key words: 1064nm laser, onychomycosis, scoring clinical index of onychomycosis (SCIO), ketoconazole ointment

CLC Number:

R756.4

CAO Yan-yun, SUN Ying-fei, XU Yang, KONG Wei, XU Shun-ming. Clinical observation of long-pulsed 1064nm laser combined with ketoconazole ointment in the treatment of onychomycosis[J]. Chinese Journal of Mycology, 2019, 14(3): 154-158.

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