Clinical analysis of 20 cases of dermatophytes caused by Microsporum canis and literature review

Abstract

Abstract:

Objective To investigate the clinical characteristics of Microsporum canis infections according to analysis of 20 cases and literature review of the last ten years.Methods Microsporum canis infections were diagnosed by mycological examinations.The general information of patients,the characteristics of skin lesions,course of disease,treatment and prognosis were analyzed and the literature review of the last ten years was also performed.Results There were 302 patients in outpatient diagnosis and literature review who aged 17 days to 83 years,Male to female ratio was about 1:2,80% of patients had a history of exposure to pets.Clinical manifestations of children mostly were tinea capitis,while the adults were mostly tinea corporis.Diagnosis was based mainly on mycological microscopy and culture.The prognosis was good after antifungal therapy.Conclusion Tinea coursed by Microsporosis canis is a common dermatophytosis,which has high incidence and strong contagion.Once diagnosed,we should standardize treat and give patient education timely in order to prevent spread and reduce morbidity.

Key words: Microsporum canis, Microsporum lanosum, tinea capitis, tinea corporis

CLC Number:

R756

CAO Yan-yun, XU Shun-ming. Clinical analysis of 20 cases of dermatophytes caused by Microsporum canis and literature review[J]. Chinese Journal of Mycology, 2017, 12(1): 29-33,44.

References

[1] 喻楠,王琪.犬小孢子菌同时引起体癣和甲真菌病的观察[J].宁夏医学院学报,2007,29(3):315-316.
[2] 王竞杰,章强强.犬小孢子菌病67例临床观察[J].中国真菌学杂志,2006,1 (3):156-157.
[3] 景东云.不典型泛发性体癣误诊银屑病1例[J].中国真菌学杂志,2007,2(1):35.
[4] 李东明,陈学荣.饲养遗弃猫致泛发性体癣1例报告[J].中国真菌学杂志,2007,2(4):220-221.
[5] 高志琴,李佳琳,顾伟鸣.婴儿头癣1例[J].临床皮肤科杂志,2007,36(5):322-323.
[6] 谢小元,赖维,龚子鉴,等.犬小孢子菌致人猫共患体癣1例[J].2008,37(6):405.
[7] 高峰,李灵云.儿童体癣误诊病例1例[J].中国真菌学杂志,2009,4(6):361-362.
[8] 王芳,李莉,窦侠,等.犬小孢子菌致成人头癣、体癣和急性角结膜炎[J].临床皮肤科杂志,2009,38(3):175-177.
[9] 尹兴平,张海平,杨莉佳.犬小孢子菌致脓癣1例[J].中国麻风皮肤病杂志,2009,25(1):76-77.
[10] 张晓辉,张静,薛汝增,等.须癣毛癣菌和犬小孢子菌共同致面癣1例[J].岭南皮肤性病科杂志,2009,16(6):400-401.
[11] 江光明,陆原,邱茗.幼儿两兄弟同时感染犬小孢子菌[J].中国真菌学杂志,2009,4(5):303-304.
[12] 胡素泉,王淼淼,沈永年,等.15例人畜共患体癣的临床分析[J].中国真菌学杂志,2010,5(3):154-157.
[13] 王洁,徐彦春,鞠荚,等.犬小孢子菌致新生儿头癣3例[J].西北国防医学杂志,2013,2(1):6.
[14] 冯姣,王雪连,刘娟,等.犬小孢子菌致体癣1例[J].中国真菌学杂志,2012,7(5):302-303.
[15] 马越娥,顾俊瑛,高飞,等.30例犬小孢子菌致体癣病例的临床分析[J].中国真菌学杂志,2013,8(2):90-92.
[16] 刘伟霞,刘伟,陈伟,等.犬小孢子菌致成人结缔组织病患者头癣一例[J].实用皮肤病学杂志,2013,6(2):116-117.
[17] 杨虹,高志琴,陈健,等.犬小孢子菌致皮肤癣菌病162例回顾分析[J],中国真菌学杂志,2013,8(4):217-219.
[18] 曾梅华,倪杏艳,刘芳,等.犬小孢子菌致人狗共患体癣1例[J].中国麻风皮肤病杂志[J].2013,29(12):786-787.
[19] 高晖,岳颖.犬小孢子菌致头癣合并体癣1例[J].中国麻风杂志,2013,29(7):473-474.
[20] 李宗辉,吴凡,邓琳,等.宠物猫致夫妻共患犬小孢子菌体癣[J].中国真菌学杂志,2014,9(5):296-297.
[21] 王春富.人畜共患的犬小孢子菌病[J].畜牧兽医科技信息,2012,14(2):34-35.
[22] 王洁,陈起科,杜华,等.羊毛状小孢子菌病199例[J].西北国防医学杂志.1999,20(1):47.
[23] Lee WJ,Song CH,Lee SJ,et al.Decreasing prevalence of Microsporum canis infection in Korea:through analysis of 944 cases(1993-2009)and review of our previous data(1975—1992)[J].Mycopathologia,2012,173(4):235-239.
[24] 李彩霞,刘维达.我国大陆近年儿童头癣流行情况的回顾分析[J].中国真菌学杂志,2011,6(2):77-80.
[25] Ameen M.Epidemiology of superficial fungal infections[J].Clin Dermatol,2010,28(2):197-201.
[26] Coaez AC,de Souza JV,Sadahiro A,et al.Frequency and aetiology of dermatophytosis in children age 12 and under in the state of Amazonas,Brazil[J].Rev Iberoam Micol,2012,29(4):223-226.
[27] Buckley DA,Fuller LC,Higgins EM,et al.Lesson of the week.Tinea capitis in adults[J].BMJ,2000,320(7246):1389-1390.
[28] Gupta AK,Summerbell RC.Tinea capitis[J].Med Mycol,2000,38(4):255-287.
[29] Mansur AT,Artunkal S,Ener B Tinea capitis in an adult patient under treatment with trastuzumab[J].Mycoses,20l1,54(5):e609-610.
[30] 郑岳臣,邬焱卿,陈辉.犬小孢子菌入侵头发模式及其体外生长繁殖的观察[J].中华皮肤科杂志,2006,39(8):451-453.
[31] 潘万俊.某院浅部真菌病及其病原菌分布[J].中国感染控制杂志,2014,13(6):374-377.
[32] 王学军.儿童头癣病原菌及药敏试验分析[J].检验与诊断,2013,12(1):116-117.
[33] 陈洁,李志刚.伊曲康唑与特比萘芬治疗儿童头癣疗效观察[J].临床皮肤科杂志,2003,32(3):165.
[34] 路永红,周培媚,苏晓杰,等.特比萘芬治疗儿童头癣59例疗效和安全性评价[J].中国皮肤性病学杂志,2008,22(12):768.
[35] 佟盼琢,杨晓亮,冯琴,等.盐酸小檗碱联合抗真菌药物对犬小孢子菌体外抗菌活性的研究[J].临床皮肤科杂志,2011,40(7):391-393.
[36] Khosravi AR,Shokri H,Sohrabi N.Potential effects of Trachyspermum copticum essential oil and propolis alcoholic extract on Mep3 gene expression of Microsporum canis isolates[J].J Mycol Med,2014,24 (3):101-107.
[37] Arena R,Toussaint S,Isa-Isa R.Kerion and dermatophytic granuloma.Mycological and histopathological findings in 19 children with inflammatory tinea capitis of the scalp[J].Int J Dermatol,2006,45(3):215-219.