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Chinese Journal of Mycology 2016, Vol. 11  Issue (4): 243-247,242.

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Candida glabrata: review of epidemiology and antifungal susceptibility

HOU Xin1, XU Ying-chun1, ZHAO Yu-pei2   

  1. 1. Department of Clinical Laboratory, Peking Union Medical College Hospital, Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China;
    2. Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China
  • Received:2015-12-31 Online:2016-08-28 Published:2016-08-28

Abstract:

Candida glabrata is a pathogenic yeast and the one of the most frequent causative agent of invasive candidiasis.The difficulties arise from its high resistance to azole antifungals.So echinocandins are often used as first-line therapy for C.glabrata invasive infection.However,reports of C.glabrata resistant to both azoles and the echinocandins are of concern.Molecular typing of C.glabrata could provide information on nosocomial transmission and strain variation.Thus,this review intends to present an excerpt of the biology,epidemiology,molecular typing and antifungal susceptibility carried out up to the present.

Key words: Candida glabrata, epidemiology, molecular typing, antifungal susceptibility

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