Clinical and etiologic features in 52 oral candidiasis patients with HIV/AIDS

Abstract

Abstract:

Objective Oral candidiasis is considered one of the most common oral diseases of Human Immunodeficiency Virus /Acquired Immune Deficiency Syndrome patients.Understanding the clinical and etiologic features of the disease plays a vital role in its diagnosis and use of medication.Methods Mucosal swab samples were collected from 70 HIV/AIDS patients with oral candidiasis.And yeast colonies were developed and identified by CHROMagar Candida.Results There were 52 cases of oral candidiasis with 70 HIV/AIDS patients,mainly manifested in Pseudomembranous and erythema types,of which Pseudomembranous is the most common.The detection rate of Candida albicans was the highest (60.32%) in patients with oral candidiasis HIV/AIDS.Other identified Candida species were C.tropicalis (19.05%),C.glabrata (12.70%) and C.crusei (7.94%).There were 9 cases of oral candidiasisin of HIV/AIDS patients with mixed infection and 2 cases with three kinds of pathogenic bacterias.Conclusion The Clinical manifestation of HIV/AIDS patients with oral candidiasis is complex and concurrent.However,diagnosing based merely on its clinical appearance of the disease is insufficient.Therefore,accurate classification of pathogenic bacterias can guide the usage of clinical medication and reduce the production of drug resistant bacterias.

Key words: oral candidiasis, HIV/AIDS patient, Candida albicans, Clinical phenotype

CLC Number:

R756.5

LI Ze-hui, LI Gang, XUE Rui. Clinical and etiologic features in 52 oral candidiasis patients with HIV/AIDS[J]. Chinese Journal of Mycology, 2015, 10(3): 154-157.

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