Abstract:

Objective To detect antagonistic activity of fungal strains isolated from the extreme environment against Microsporum canis and Sporothrix.Method The 24 fungal strains were isolated from the extreme environment, and then the supernatants of their cultures were extracted, for exploring the antagonism for clinical pathogenic fungi such as Microsporum canis and Sporothrix sp. according to M38-A2 and E-test criterion.Results A total of 8 fungal strains' supernatants showed that diameters of bacteriostatic circles are equal or greater than 1.0 cm, which revealed evident antagonistic activity to Sporothrix sp. Similarly, 9 fungal strains' supernatants show evident antagonistic activity to Microsporum canis due to the diameters of bacteriostatic circles are equal or greater than 1.0 cm. The antagonism results revealed 90% of correlation in antagonism test using these two different fungal species. Seventy pencents of the fungal supernatants and the mycelium extracts of extreme environment fungi showed antagonistic activity for Microsporum canis and Sporothrix sp..Conclusion Some extreme environment fungi have antagonistic activites for Microsporum canis and Sporothrix.

Key words: extreme environment, fungi, antagonism