Abstract: Objective To observe the curative efect of Compound Kushen Lotion plus itraconazol capsule in the treatment of malassezia folliculitis.Methods 48 cases of patients with malassezia folliculitis were divided into treatment group (24 cases) and control group (24 cases).Both two groups were treated with oral itraconazol capsule 200 mg,once a day for 2 weeks;treatment group were treated with additional Compound Kushen Lotion (external application),twice a day for 4 weeks.All the patients observed the curative efect and retested the microscopic fungi 2 weeks and 8 weeks later from the first day they have medicine.Results After 2 week's treatment,the total efectiveness of treatment group (75.0%) was higher than control group (41.7%). The difference was statistically significant (χ²=5.49,P<0.05).At 8 weeks,the total efectiveness of treatment group (91.7%) was higher than control group (62.5%). The difference was statistically significant (χ²=5.78,P<0.05).Conclusion The curative effect of Compound Kushen Lotion plus itraconazol capsule in the treatment of patients with malassezia folliculitis is significant,and it can be generalized.

Key words: Compound Kushen Lotion, itraconazol, malassezia, folliculitis