Research progress of Chinese herbal medicine against Candida albicans

Abstract

Abstract: Candida albicans is one of the most common human fungal pathogen, which can cause a variety of superficial and deep mycoses,and often become resistant to commonly used antifungal agents. So looking for broad-spectrum, high efficiency, low toxicity anti-Candida drugs has became a hot research. Extremely rich resources of Chinese herbal medicine have certain advantages of the prevention and treatment of Candida infections. To study the role of Chinese herbal medicine against Candida albicans,articles summarize the three aspects: herbal mechanism of action against Candida albicans and its active ingredient, single herb and compound herbal preparations against Candida albicans,synergistic effect of compound traditional Chinese medicine and western medicine against Candida albicans.The Chinese herbal medicine against Candida albicans clinical and experimental studies in recent years were reviewed. The article further confirmed the role of herbal anti-Candida albicans and showed the broad application prospects of herbal antifungal aspects.

Key words: Candida albicans, Chinese herbal medicine, research progress

CLC Number:

R379.4 978.5

LI Shu-yi, XIA Zhi-kuan, YANG rong-ya. Research progress of Chinese herbal medicine against Candida albicans[J]. Chinese Journal of Mycology, 2013, 8(3): 185-187.

References

[1] 陆承平.兽医微生物学[M].北京:中国农业出版社,2005.
[2] 谢小梅,许杨.抗真菌中药的作用机理研究进展[J].中国中药杂志,2004,29(3):200-201.
[3] 董小青,刘丽英,陈虹,等.土槿乙酸抗白念珠菌的敏感性及作用机理的电镜研究[J].天津药学,2008,20(2):1-3.
[4] 李大宁,吴建华,陈德利,等.流式细胞术测定3种中药提取物对白念珠菌胞核的影响[J].临床皮肤科杂志,2003,31(5):287-289.
[5] 谢婷,范瑞强,吴盘红. 中药干预白念珠菌的实验研究进展[J].皮肤性病诊疗学杂志,2012,19(3):192-194.
[6] 汪长中,韩宁,徐振华,等.穿心莲内酯诱导白念珠菌生物膜分散细胞凋亡的研究[J].中国中药杂志,2012,37(3):362-364.
[7] 张超,雷春娟,魏琴,等.复方中药提取物抗白念珠菌活性及其主要成分[J].湖北农业科学,2011,50(10):2000-2002.
[8] 黄江涛. 抗真菌单味及复方中药试验研究进展[J].河北中医,2012,34(9):1426-1428.
[9] Liu Q,Luyten W,Pellens K,et al. Antifungal activity in plants from Chinese traditional and folk medicine[J].Journal of Ethnopharmacology,2012,143: 772-778.
[10] 张国哲,苏昕. 132 味中药水提物对 8 种致病真菌抑菌活性的筛选[J].辽宁中医杂志,2012,(39)9:1834-1837.
[11] 刘涛峰,郑玉荣,刘小平,等. 10种中药水煎剂对念珠菌的体外抑菌作用[J].安徽中医学院学报,2012,31(4):72-74.
[12] Wei GX,Xu X,Wu CD. In vitro synergism between berberine and miconazole against planktonic and biofilm Candida cultures[J].Archive Oral Biol,2011,56:565-572.
[13] 蔡文科,常洪,樊冬梅,等. 中西医结合治疗念珠菌性外阴阴道炎疗效观察[J].中国真菌学杂志,2008,3(2):88-89.
[14] 张石群,林辉,苗琦,等. 覆盆子提取物联合唑类药物抗真菌活性研究[J].中国真菌学杂志,2012,7(1):4-7.
[15] 林滔,黄宁. 中草药体外抗真菌活性实验方法分析[J].中国药师,2006,9(1):66-67.