Abstract: Objective To investigate wether the genital candidiasis is resulted from the same pathogenic fungus between the couple and to guide the clinic treatment by drug sensitivity test.Methods Use common ways to cultivate candida. API 20C AUX and the microdilution method were used to do identification and drug sensitivity test of candida.Results Eighty-eight genital candida strains were isolated. Fouty-one couples surffered from the same candida, which was significant diffrence compared with the control (P<0.05) Eighty-eight genital candida strains were senstive to nystatin and clotrimazole,but showed different drug resistence with itraconazole and fluconazole.Conclusion When one of the couple suffer from genital candidias, the other should have detail examination and individual therapy in order to reduce the rate of recurrence.

Key words: genital candidias, vulvoaginal candidias, sexual transmission, drug senitive test