Abstract: Objective To analyze the clinical features, pathogenic fungus distribution and correlation between fungus and clinical patterns of onychomycosis with positive fungal culture in 637 cases.Methods Fungal culture and clinical analysis were performed on 637 cases of onychomycosis with positive result by fungal cultivation.Results DLSO were the most frequently clinical patterns. Of all the 637 cases of onychomycosis with positive fungal culture. The rates of dermatophytes, yeasts and non-dermatophytic moulds were 69.39%,18.68% and 11.93% respectively. There are differences between patients with different sex and age. Dermatophytes were the dominate strains.Conclusion In Northwest Beijing region, the dominant clinical type of onychomycosis with positive fungal culture is DLSO. The most frequent pathogenic fungus of onychomycosis is Trichophyton spp.

Key words: onychomycosis, pathogen, dermatophyte, yeast, mould