Abstract: Objective To investigate the efficacy of compound ciclopirox olamin spray in the treatment of superficial mycosis.Method Compound ciclopirox olamin spray was applied in stage Ⅰonce daily for 4 weeks.In stage Ⅱ,double-blind,randomized controlled trial was conducted.Compound ciclopiroxolamin spray and compound ciclopirox olamin with triamcinolone acetonide spray were applied in the group A and B respectively for 4 weeks(once daily).Results The total effective rate in groupⅠwas 80%by the end of the treatment.The total effective rates in group Ⅱ A and group Ⅱ B were 75%versus 82.35%,94.74%versus 100%at week 2 and week 4,respectively.The efficacy of compound ciclopirox olamin spray in the treatment of superficial mycosis was similar to that of compound ciclopirox olamin with triamcinolone acetonide spray(P>0.05).Conclusions Compound ciclopirox olamin spray is effective and safe in the treatment of superficial mycosis,with obvious pruritus relieving and fewer local irritation.

Key words: ciclopirox olamin, superficial mycosis, curative effect