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Chinese Journal of Mycology 2011, Vol. 6  Issue (6): 337-340.

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TLR2 expression in rats with Candida albicans infection in lung

LIN Li, WANG Li, ZHOU Yang-yang, CHEN Yao-hua, MENG Xin-li, KANG Jian   

  1. Department of respiratory, the first affiliated hosipital of China Medical University, Shenyang, 110001, China
  • Received:2011-08-01 Online:2011-12-28 Published:2011-12-28

Abstract: Objective To explore the expression of TLR2 in rats with Candida albicans infection in lung.Method Rats model of Candida albicans infection in lung was set up and changes in pathology were observed.TLR2 expression in the tissues at different timepoints were also observed by immunohis to chemical method.Results The expression of TLR2 in the lung of Candida albicans infected rats was significaltly higher than that in healthy rats.Conclusions Over expression of TLR2 in Candida albicans infected rats may related to inflammatory reaction.

Key words: Candida albicans, infection, Toll like receptor2

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