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Chinese Journal of Mycology 2023, Vol. 18  Issue (1): 33-37,57.

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Clinical value of rapid on site evaluation in the diagnosis of pulmonary cryptococcosis

WANG Hansheng, CHEN Dan, REN Tao, YOU Hui, WEI Na, LUO Guoshi, WANG Meifang   

  1. Department of Pulmonary and Critical Care Medicine, Taihe Hospital, Hubei University of Medicine, Shiyan 442000, China
  • Received:2021-09-01 Published:2023-03-17

Abstract: Objective To explore the accuracy and timeliness of rapid on-site evaluation site (ROSE) in the diagnosis of pulmonary cryptococcosis by percutaneous lung biopsy. Methods A retrospective analysis of 25 cases of percutaneous lung biopsy pathologically diagnosed as pulmonary cryptococcus, including patient imaging, ROSE and pathological diagnosis results, time-consuming, and diagnosis costs was performed. Results Based on the final diagnosis, and the accuracy, sensitivity, and specificity of ROSE were 80%, 80%, and 100%, respectively. The average time for the issuance of ROSE and pathology reports were (10±1) min and (81±1.4) h, respectively; the diagnosis cost were 220 and 450 yuan, respectively. Conclusion ROSE had high accuracy and timeliness in the diagnosis of Cryptococcus neoformans pneumonia, and economic cost savings. It is worthy of application and promotion in the diagnosis of cryptococcus neoformans pneumonia in respiratory intervention.

Key words: pulmonary cryptococcosis, rapid on-site evaluation, histopathology, percutaneous lung puncture

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