Drug use evaluation of caspofungin based on weighted TOPSIS method

Abstract

Abstract: Objective Establish the detailed rules for the evaluation of rational drug use of caspofungin to promote the rational use in clinical practice. Methods A retrospective study was conducted to screen and archive the medical records of caspofungin in the First People's Hospital of Yancheng from 2021.1-2021.12, and the weighted approximation ideal solution ranking method was used for review. Results A total of 93 qualified cases were screened, including 23 reasonable cases (Ci≥0.8), accounting for 24.73%; 51 basically reasonable cases (0.8>Ci ≥ 0.6), accounting for 54.84%; 19 unreasonable cases (Ci<0.6), accounting for 20.43%. Conclusion The evaluation of the use of caspofungin by weighted approximation is feasible. The evaluation results show that there are still problems in the use of caspofungin in this hospital, and the rectification should be strengthened.

Key words: weighted TOPSIS method, caspofungin, pediatrics, drug use evaluation

CLC Number:

R978.5

HUANG Lei, ZHANG Yaming, YIN Cunlin, MIAO Yang, QI Wang, WANG Aming. Drug use evaluation of caspofungin based on weighted TOPSIS method[J]. Chinese Journal of Mycology, 2022, 17(3): 200-204,230.

References

[1] 马永超,张晓艳,陈传欣,等.血液肿瘤患者侵袭性真菌感染的流行病学特征[J].江苏医药,2015,41(5):512-513,516.
[2] 夏迪,施毅.棘白菌素类药物的药动学和药效学指导临床用药优化[J].中国感染与化疗杂志,2015,15(4):383-386.
[3] 中国医师协会血液科医师分会,中国侵袭性真菌感染工作组.血液病/恶性肿瘤患者侵袭性真菌病的诊断标准与治疗原则(第六次修订版)[J].中华内科杂志,2020,59(10):754-763.
[4] 吴秀文,任建安.中国腹腔感染诊治指南(2019版)[J].中国实用外科杂志,2020,40(1):1-16.
[5] 《抗菌药物临床应用指导原则》修订工作组.抗菌药物临床应用指导原则(2015年版)[M].北京:人民卫生出版社,2015.
[6] SCHELENZ S, BARNES R A, BARTON RC,et al. British Society for Medical Mycology best practice recommendations for the diagnosis of serious fungal diseases[J]. Lancet Infect Dis, 2015, 15(4):461-474.
[7] HAGE C A,CARMONA E M, EPELBAUM O, et al. Microbiological laboratory testing in the diagnosis of fungal infections in pulmonary and critical care practice. an official American Thoracic Society clinical practice guideline[J].Am J Respir Crit Care Med, 2019, 200(10):535-550.
[8] Gilbert D N,Chambers H F,Eliopoulos G M,et al.热病·桑福德抗微生物治疗指南[M].第48版.范洪伟主译.北京:中国协和医科大学出版社,2019:83.
[9] 吴文娟,钦光跃,李志军,等.伏立康唑片联合卡泊芬净注射剂治疗血液病合并侵袭性肺部曲霉菌属感染的临床研究[J].中国临床药理学杂志,2017,33(19):1855-1857,1861.
[10] 陈旭,何仁,杨希,等.卡泊芬净药物利用评价标准的建立及应用[J].中国临床药学杂志,2020,29(3):211-215.
[11] 乔智灏,李嘉莹,刘昶.卡泊芬净对重症侵袭性假丝酵母菌感染降阶梯治疗的效果评价[J].西北药学志,2021,36(5):812-815.
[12] 于文征,王学霞,孙建荣,等.卡泊芬净经验性治疗白血病并发真菌感染的临床疗效分析与评价[J].中华医院感染学杂志,2012,22(15):3360-3361.
[13] 陈迁,陈孟莉,贾宁,等.抗真菌药米卡芬净及卡泊芬净在造血干细胞移植患者中的临床应用及评价[J].中华医院感染学杂志,2012,22(2):380-382.[14] 王玲.卡泊芬净治疗儿童血液病侵袭性真菌感染的疗效及安全性评价[J].中华临床医师杂志(电子版),2012,6(22):7398-7400.[15] 李建明,刘庆欧,曲成毅.综合评价中两种指标权重的确定方法--相似权法和属性AHM赋权法[J].山西医药杂志,2004, 33(6):492-494.[16] NGUYEN T H, HOPPE-TICHY, GEISS H K, et al. Factors influencing caspofungin plasma concentrations in patients of a surgical intensive care unit[J]. J Antimicrob Chemother, 2007, 60(1):100-106.[17] 冉烁,俞吉,朱裕林.应用加权TOPSIS法评价某院伏立康唑使用情况[J].实用医药杂志,2020,37(7):636-641.[18] 胡章海,杨万枝,邬皓,等.基于加权逼近理想解排序法的儿科利奈唑胺药物利用评价.中国药物警戒,1-7. http://kns.cnki.net/kcms/detail/11.5219.R.20210723.1301.002.html.[19] 宋林,田维金,季欢欢,等.基于加权逼近理想解排序法的万古霉素新生儿药物利用评价[J].中国新药与临床杂志,2016,35(5):369-373[20] 王桂凤,刘锐锋,李雪芹,等.基于加权TOPSIS法的注射用哌拉西林钠他唑巴坦钠药物利用评价[J].中国医院药学杂志,41(1):52-56.[21] 冉烁,俞吉,朱裕林.应用加权TOPSIS法评价某院伏立康唑使用情况[J].实用医药杂志,2020,37(7):636-641.[22] PAPPAS P G, KAUFFMAN C A, ANDES D R, et al. Executive summary:clinical practice guideline for the management of candidiasis:2016 update by the Infectious Diseases Society of America[J].Clin Infect Dis, 2016, 62(4):409-417.[23] 刘又宁,解立新.感染相关生物标志物临床意义解读专家共识[J].中华结核和呼吸杂志,2017,40(4):243-257.