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Chinese Journal of Mycology 2021, Vol. 16  Issue (3): 184-187.

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A case of Chromoblastomycosis caused by Fonsecaea monophora in Hainan fisherman

NIU Mu1, LIAO Wanqing2, WU Weiwei1, ZHENG Wenai3   

  1. 1. Department of Dermatologic surgery/Pathology, The fifth people's hospital of Hainan Province, Haikou 571101, China;
    2. Department of Dermatology, Second Affiliated Hospital of Naval Medical University, Shanghai 200003, China;
    3. Department of Laboratory Medicine, The fifth people's hospital of hainan province, Haikou 571101, China
  • Received:2020-12-14 Online:2021-06-28 Published:2021-06-28

Abstract: Here we report a case of chromoblastomycosis caused by Fonsecaea momophora. A 80-year-old man was admitted to the hospital with a more than eleven years’s history of plaque on the right hand. Direct microscopic examination and fungal culture, histopathologic examination, ribosomal internal transcribed spacer (ITS) sequence analysis were performed. The thick-walled, brown sclerotic bodies were observed by direct microscopic examination and histopathological examination. Fungal culture yielded black brown villiform colonies and rhinocladiella type and cladosporium type conidia were observed in the slide culture. The isolate was identified as Fonsecaea momophora according to the ITS sequencing. The patient was prescribled itraconazole(200 mg/d) combined with terbinafine (250 mg/d) for 4 months.The lesions improved greatly and the patient was now under followed-up.

Key words: Fonsecaea monophora, chromoblastomycosis, itraconazole, terbinafine, subcutaneous mycoses

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