Abstract: Objective To report the first case of endophthalmitis caused by Paraconiothyrium cyclothyrioides in China and analyze the fungal biological characteristics, infection routes and treatment. Methods The strain was isolated from anterior chamber sediment of the injured left eye, and was identified based on growth temperature, microscopic morphologies and ITS sequence analysis. Results The strain grew well at 25℃, and the macroscopic morphology on PDA showed a woolly grayish-white colony and folded surface. But the strain grew slowly at 35℃ with soybean-size white convex colony. After cultivation at 25℃ and 35℃ numerous nodular hyphae were found under the microscope, and no conidia were observed. ITS sequence analysis showed the strain was Paraconiothyrium cyclothyrioides. Conclusion This was the first report of endophthalmitis caused by Paraconiothyrium cyclothyrioides in China.

Key words: endophthalmitis, fungal, inflammation, Paraconiothyrium cyclothyrioides