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Chinese Journal of Mycology 2021, Vol. 16  Issue (2): 128-130,140.

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A case of disseminated Talaromyces marneffei

WU Rongqun1, XU Wenying1, LI Lili1, CHEN Xingchun2, WEI Haiming3, XIE Zhi1   

  1. 1. Guangxi Zhuang Autonomous Region People's Hospital, Department of Dermatology, Nanning 530000, China;
    2. Guangxi Zhuang Autonomous Region People's Hospital, Department of Laboratory Medicine, Nanning 530000, China;
    3. Guangxi Zhuang Autonomous Region People's Hospital, Department of Pathology, Nanning 530000, China
  • Received:2020-06-05 Published:2021-04-25

Abstract: A 32-year-old man was admitted because of recurrent episodes of lymphadenectasis, fever and skin rashes for two years. Broad-spectrum antibiotics and anti-tuberculosis therapy were ineffective. Lung CT showed multiple nodules in both lungs and the serum was positive for anti-IFN-γ. Disseminated Talaromyces marneffei was diagnosed by skin biopsy, lymph node biopsy, lung biopsy. Amphotericin B liposome combined with voriconazole had a good therapeutic effect.

Key words: Talaromyces marneffei, non-HIV patient, anti-IFN-γ autoantibody

CLC Number: