Trichosporon asahii sepsis in a patient with acute myeloid leukemia and literature review

Abstract

Abstract: A case of acute leukemia with high fever during myelosuppression stage after chemotherapywas treated by broad-spectrum antibiotics. But high fever arose again after the patient's body temperature being improved. The first febrile blood culture result showed Streptococcus mitis/Staphylococcus. Trichosporon asahii was found in the second febrile blood culture. Serum cryptococcal antigen test (immunocolloidal gold method) was positive, chest CT showed lung infection. After the addition of domestic voriconazole, the body temperature once dropped and rose again. The patient who switched to imported voriconazole did not have fever again, and continued to take voriconazole orally. After 2 months, the chest CT lung lesions improved.

Key words: acute leukemia, Trichosporum asahii, bloodstream infection

CLC Number:

R519.8

YE Li, GAO Lingsu, DING Meiqi, WANG Lu. Trichosporon asahii sepsis in a patient with acute myeloid leukemia and literature review[J]. Chinese Journal of Mycology, 2021, 16(2): 125-127.

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