Clinical application of terbinafine in the treatment of subcutaneous and deep mycosis

Abstract

Abstract: Terbinafine is an active allylamine antifungal agent with a mechanism of inhibiting squalene epoxidase in the fungal cell membrane. Its spectrum of in vitro fungicidal activity includes a broad range of dermatophyte, filamentous, dimorphic fungi, and some yeast species. Terbinafine had been widely used as the first-line treatment for superficial dermatophyte infection. In nearly two decades, terbinafine also had been proved to be highly effective and safe for a variety of subcutaneous and deep fungal infections, either in monotherapy or in combination therapy.

Key words: terbinafine, subcutaneous fungal infection, deep mycosis

CLC Number:

R978.5
R.519

ZHU Hong-mei, WEN Hai. Clinical application of terbinafine in the treatment of subcutaneous and deep mycosis[J]. Chinese Journal of Mycology, 2020, 15(6): 374-377.

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