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Chinese Journal of Mycology 2019, Vol. 14  Issue (5): 316-320.

Original articles Previous Articles    

Advance on Traditional Chinese Herb in the topical antifungal therapy

ZHU Hong-mei1, WEN Hai1, LI Bin2   

  1. 1. PLA Key Laboratory of Fungal Diseases, Department of dermatology, Changzheng Hospital, Shanghai 200003;
    2. Yueyang Hospital, Shanghai University of TCM, Shanghai 200437
  • Received:2019-03-08 Online:2019-10-28 Published:2019-10-28

Abstract:

Advance on topical antifungal traditional Chinese herb mainly focused on the following aspects:clinical application of empirical traditional Chinese medicinal formulae, identification and purification of monomers with antifungal function, in vitro antifungal sensitivity assay of monomers, in vivo application of new Chinese herb formulae or compound monomers products on the animal models of superficial mycosis, etc. The herbs themselves and their active ingredients might show direct or synergistic antifungal effects. Furthermore, they might reduce inflammation and relieve itching symptom through their traditional "Heat-Clearing and Dampness-Removing and Itching-Relieving" mechanisms. While eliminating some pathogenic fungi, they also made the local body microenvironment not beneficial for fungal growth.

Key words: Traditional Chinese Medicine, topical therapy, mycosis

CLC Number: