Research on functions of mononuclear cells in fungal infection

Abstract

Abstract:

Monocytes participate in the inflammatory response and activate at the site of microbial infection. However, the specific antifungal effect of monocytes is still unclear. Monocytes are heterogeneous and present in multiple subsets that play different roles in immune system. This article aims to investigate the functions of different phenotypic mononuclear cells in fungal infections (such as Candida, Cryptococcus and Aspergillus fumigatus) and provides new idea for understanding the mechanism of antifungal immunity, and monitoring fungal diseases.

Key words: monocytes, heterogeneity, fungal infection

CLC Number:

R519

DONG Jia-cheng, LIANG Guan-zhao, LIU Wei-da. Research on functions of mononuclear cells in fungal infection[J]. Chinese Journal of Mycology, 2018, 13(4): 244-246.

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