Systematic review of infections caused by Chaetomium spp.

Abstract

Abstract:

Objective Perform systamic review on Chaetomium infection case reports in literature. Methods Descriptive analysis was done with Chaetomium infection case reports over the world during recent thirty years. Results 35 patients in 29 literatures were analyzed. Every age group was involved world-widely, with young-and-middle age dominated and more males than females. 100% patients of invasive infections had a primary disease or inducement, responsed poorly to amphotericin B. The mortality rate was 85.71%. The course of most superficial infections was chronic, with a total effective rate of 66.67%. All cases were confirmed by fungal culture. Most invasive infections were coursed by C. globosum (28.57%), C. strumarium (21.43%), C.atrobrunneum (14.29%) and C. perlucidum (14.29%), while C. globosum (66.67%) was the main pathogen of superficial infections. Conclusion Chaetomium can cause various infections, which clinical features are different among different rejoins involved. Histopathology and mycological examination is beneficial for diagnosis. Physicians should pay more attention to specific fungal infection.

Key words: Chaetomium, fungal infection, systematic review

CLC Number:

R519.8

HUANG Qin, SUN Ke-xin, LI Dong-ming. Systematic review of infections caused by Chaetomium spp.[J]. Chinese Journal of Mycology, 2018, 13(1): 34-39.

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