Trichosporon asahii could growunder iron-restricted condition through siderophore secretion

Abstract

Abstract:

Objective To investigate the mechanism of the growth of Trichosporon asahii under iron-restricted condition,and provide laboratory evidence for the combined therapy with antifungals against disseminated trichosporonosis.Methods 200 μmol/L BPS was added to the YPD medium to prepare iron-restricted condition,then the growth curve of Trichosporon asahii in this medium was detected. Results The Trichosporon asahii grew normally under the iron-restricted condition,and siderophore was detected from the culture medium supernatants simultaneously. Conclusions Trichosporon asahii grew normally under the iron-restricted condition through siderophore secretion.

Key words: Trichosporon asahii, siderophore, iron

CLC Number:

R379.9

SUN Wei, DENG Juan, SU Jian-rong. Trichosporon asahii could growunder iron-restricted condition through siderophore secretion[J]. Chinese Journal of Mycology, 2018, 13(1): 1-3.

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