Developments of MALDI-TOF MS in identification of clinical filamentous fungi

Abstract

Abstract:

Invasive infections caused by filamentous fungi have been increasing in recent years.Accurate identification of filamentous fungi isolates has important role in clinical treatment of filamentous fungi infections owing to the great variety of antifungal susceptibility profiles among different species of those microorganisms.Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) has been revealed to be an emerging technology in the field of microbe identification and performed outstandingly in bacteria and yeasts identification.The performance of this novel technology in filamentous fungi identification,however,remained inferior and less-employed than that in bacteria and yeasts identification.This paper reviews some representative research aiming on working this dilemma out in the global and the remarkable developments obtained during this process.

Key words: MALDI-TOF MS, filamentous fungi, identification

CLC Number:

R379

LI Ying, XU Ying-chun. Developments of MALDI-TOF MS in identification of clinical filamentous fungi[J]. Chinese Journal of Mycology, 2017, 12(6): 378-381.

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