The recent progresses of anti-cancer fungal extracts

Abstract

Abstract:

This review summaries theadvance in anti-cancer fungal extracts in recent years.On the one hand,related multiple mechanisms might include the anti-cancer fungal extracts inducing apoptosis,inhibiting proliferation and angiogenesis.On the other hand,the anti-cancer effects of various anti-cancer fungal extracts in cancer cells are also reviewed.These study show that anti-cancer fungal extracts can inhibit the proliferation of cancer cells and induce apoptosis in cancer cells.The mechanisms of those functions involved various signal pathways,including Wnt,NK-κB,MAPK and Mitochondria related apoptosis signal pathways,and related to various proteins related to biological activity such as p38,bcl-2,c-jun,IκB,β-catenin,Akt.

Key words: fungus, cancer, mechanisms, progresses

CLC Number:

R979.1

ZENG Xuan-hao, ZHANG Qiang-qiang. The recent progresses of anti-cancer fungal extracts[J]. Chinese Journal of Mycology, 2017, 12(3): 184-192.

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