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Chinese Journal of Mycology 2017, Vol. 12  Issue (2): 89-91.

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Colonization or infection of Scedosporium in lower respiratory tract of secondary pulmonary tuberculosis patients

ZENG Jing-si1, LI Hong-jie2, MAO Ye-hong1, LIAN Xin1, ZHENG Yue-chen1   

  1. 1. Department of Dermatology and Venereology, Union Hospital, Tongji Medical College, Huazhong Science and Technology University, Wuhan 430022, China;
    2. Department of Infectious Disease, Wuhan Medical Treatment Center, Wuhan 430023, China
  • Received:2016-12-07 Online:2017-04-28 Published:2017-04-28

Abstract:

Objective Understanding colonization or infection of Scedosporium in lower respiratory tract of secondary pulmonary tuberculosis.Methods Major pathogens of Scedosporiosis, 5 Scedosporium spp.(S.apiospermum, S.boydii, S.minutispora, S.aurantiacum and S.dehoogii), were detected in bronchoalveolar lavage fluid from the patients with secondary pulmonary tuberculosis using direct microscope examination, fungal culturing and PCR-based reverse line blot (PCR-RLB) targeting the partial β-tubulin gene.Result No Scedosporium spp.were found in 101 specimens of bronchoalveolar lavage fluid from secondary pulmonary tuberculosis patients.Conclusion Rare Scedosporium spp.colonize or infect in lower respiratory tract of secondary pulmonary tuberculosis.It implies that secondary pulmonary tuberculosis complicated by Scedosporiosis due to increasing colonization of Scedosporium spp.in the respiratory tract will be uncommon.

Key words: pulmonary tuberculosis, Scedosporium, lower respiratory tract, colonization

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