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Chinese Journal of Mycology 2016, Vol. 11  Issue (6): 381-384.

论文 Previous Articles    

A multicenter study on curative effect of 1% luliconazole cream in treatment of candidal balanoposthitis

GAO Fang-ming1, YI Jiang-hua2, YE Xing-dong1, XIAO Chang-qing1, GAO Ai-li1, LIU Yu-mei1, DAI Xiang-nong1   

  1. 1. Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou 510095, China;
    2. Department of Dermatology, The Affiliated Hospital of Guangzhou Medical University, Guangzhou 510145, China
  • Received:2016-11-14 Online:2016-12-28 Published:2016-12-28

Abstract:

Objective To investigate the curative efficiency and safety of luliconazole 1% cream in treating candidal balanoposthitis.Methods A total of 70 outpatients from department of Dermatology & STD were randomly divided into two groups.Among them,38 were given luliconazole 1% cream once a day (study group) while the others were given ketoconazole cream once a day (control group).The effect was evaluated based on scores of relief for symptoms,skin signs,and mycology inspection,while the safety was evaluated according to the side effects.Results The mycological clearance rate of 1% luliconazole cream was significantly higher than that of 2% ketoconazole cream one week after treatment (P<0.05),but there was no significant difference of clinical efficacy and mycological clearance rate between the two groups two weeks after treatment (P>0.05).No significant difference was observed between the two groups in evaluation scores of clinical effect,symptom and skin sign aspects.Conclusion The curative effect and safety for 1% luliconazole cream were comparable to those of 2% ketoconazole cream in treating candidal balanoposthitis.It is worth popularizing and applying clinically.

Key words: luliconazole, candidal balanoposthitis, curative effect

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