Abstract:

Objective To observe and evaluate the efficacy and safety of 1% luliconazole cream in the treatment of tinea pedis.Methods In a randomized,single blind,positive drug controlled study,patients selected according to experiment design were randomly divided into 2 groups,luliconazole group (1% topical luliconazole cream,1 time a day,2 weeks),control group (1% topical terbinafine cream,1 time a day,2 weeks).The evaluation of clinical and mycological efficacy was performed after 2 weeks.Results Eighty-six cases with fungal positive result were randomly divided into 2 groups,43 cases in each group.Finally 59 patients entered effect analysis.Clinical efficiency rates of luliconazole group and terbinafine group were 96.97% and 96.15% (P>0.05),fungal clearance rates were 81.82% and 80.77% (P>0.05).Conclusion It's safety and efficacy of treating tinea pedis with luliconazole cream 1%.

Key words: luliconazole, terbinafine, tinea pedis, clinical protocols, randomized controlled trials