Retrospective analysis of diabetics combined with zygomycosis in mainland China:a review of 74 cases

Abstract

Abstract:

Objective To investigate the epidemiology and clinical characteristics of diabetics combined with zygomycosis in mainland China.Methods Literatures about diabetics combined with zygomycosis in China were collected from the electrical databases,such as CNKI,CJDF,VIP,Chinese physician full-text journals,and also Pubmed since 1990.Results Fifty-seven articles(74 cases) were included in the study.Median age was 49.8(range,16-77) years old,with a male predominance(M:F=1.55:1).Without specific clinical and radiographic features,its diagnosis was mainly dependent on mycologic and/or histopathological examination.Amphotericin B was the first-line antifungal drug for diabetics combined with zygomycosis,and better efficacy could be got if combined with surgical treatment.Conclusion In recent years,there is an increasing trend in the prevalence of diabetics combined with zygomycosis in mainland china.For highly suspected diabetics combined with zygomycosis,it's necessary to initiate early anti-fungal therapy,and combined surgical treatment may improve the outcome.

Key words: zygomycosis, Mucor, diabetics, China

CLC Number:

R519.8

ZHAO Jing-yu, FANG Wei, YANG Ya-li, PAN Wei-hua, LIAO Wan-qing, TANG Yi-chen. Retrospective analysis of diabetics combined with zygomycosis in mainland China:a review of 74 cases[J]. Chinese Journal of Mycology, 2016, 11(1): 33-36.

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