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Chinese Journal of Mycology 2016, Vol. 11  Issue (1): 24-27.

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The effect of blood bacterial infection on the serum(1,3)-β-D-beta result

WANG Ming-da1, CHEN Ruo-hong2, HUANG Jia-si1, LI Jing1, WANG Ling2, LI Hui2, LIU Yin-yin2, DU Wen-han2, SHEN Ting2, LV Xing2   

  1. 1. Department of Clinical Laboratory, The Third Hospital of Changsha, Changsha 410000, China;
    2. Department of Clinical Laboratory, The Second Xiangya Hospital of Central South University, Changsha 410000, China
  • Received:2015-09-08 Online:2016-02-28 Published:2016-02-28

Abstract:

Objective To evaluate the influences of bacterial infections on the(1,3)-β-D-glucan detection.Method Serums of forty patients with identification of positive blood culture and forty patients with identification of negative blood culture,after controlling disturbance,were detected by G tests.Results Among 22 patients with Gram positive bactereamia and 18 patients with Gram negative bactereamia,only one patient identified as Escherichia coli infection was positive for G test,while four patients were G test suspicious and the rest were negative.Among 40 patients with negative blood culture,three patients were known as G test suspicious while the rest were negative.There is no statistic significance of G test results between specimens with blood culture positive and negative(P>0.05).Conclusion Bacterial infections have minor influences on G test detection in this study.

Key words: (1,3)-β-D-glucan, bacteraemia, cross reactivity

CLC Number: