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Chinese Journal of Mycology 2016, Vol. 11  Issue (1): 13-15.

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The antifungal susceptibility test in vitro of luliconazole ethosomes

FAN Jian-feng, Lin Bi-wei, Li Heng-jin   

  1. PLA General Hospital Department of Dermatology, Beijing 100853, China
  • Received:2014-12-10 Online:2016-02-28 Published:2016-02-28

Abstract:

Objective To study antifungal susceptibility of luliconazole ethosomes in vitro.Methods In vitro,antifungal activity of luliconazole ethosome,liposome,hydroalcoholic solution:MICs were determined using the micro-broth dilution assay.Results The MIC of the luliconazole ethosome was lower than that of liposome form or hydroalcoholic solution form.The MIC of luliconazole ethosome to Trichophyton spp.was lower than the sensitive degree to Candida spp.Conclusion In vitro,the antifungal effect of luliconazole ethosome is better than luliconazole liposome or its hydroalcoholic solution.

Key words: luliconazole ethosomes, dermatophytes, Candida, antifungal succeptibility

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