Progress of fungi in gut and the related diseases

Abstract

Abstract:

There were 66 fungal genera and 184 fungal species (with Candida as the dominant fungal genera) colonizing in human gastrointestinal tract.Similar to commensal bacteria,commensal fungi could be an important part of microbiome,which helps organ developing,participates of nutrients metabolism,induces immunity and triggers (or represses) inflammatory responses.When specific defense systems damaged (e.g.immune deficiency) or microbiome unbalanced (e.g.after administration of antibiotics),opportunistic pathogenic fungi could contribute to mycotic esophagitis in susceptible individuals,and might also play a role in gastrointestinal diseases such as infective colitis,irritable bowel syndrome,inflammatory bowel disease,and acute pancreatitis.

Key words: fungi, gastrointestinal, disease

CLC Number:

R57
R379

NIU Hai-jing, SU Bing-zhong. Progress of fungi in gut and the related diseases[J]. Chinese Journal of Mycology, 2015, 10(6): 377-379,384.

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