Multi-center epidemiological survey of pathogenic fungi of onychomycosis in China

Chinese Journal of Mycology　2015, Vol. 10 　Issue (4): 197-202.

Multi-center epidemiological survey of pathogenic fungi of onychomycosis in China

WANG Ai-ping¹, YU Jin¹, WAN Zhe¹, LI Fu-qiu², ZENG Jing-si³, LIU Wei-da⁴, ZHANG Qiang-qing⁵, HAO Fei⁶, RAN Yu-ping⁷, XI Li-yan⁸, LAI Wei⁹, LI Ruo-yu¹

1. Department of Dermatology & Venereology, First Hospital, Peking University, Beijing 100034;
2. Department of Dermatology, the Second Hospital of Jilin University, Changchun 130041;
3. Department of Dermatology & Venereology, Union Hospital, Tongji Medical College, Huazhong Science and Technology University, Wuhan 430022;
4. Department of mycology, Insitute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing 210042;
5. Department of Dermatology, Huashan Hospital, Fudan University, Shanghai 200040;
6. Department of Dermatology and Venereology, Southwest Hospital, Third Military Medical University, Chongqing 400038;
7. Department of Dermatology and Venereology, West China Hospital, Sichuan University, Chengdu 610041;
8. Department of Dermatology, the Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120;
9. Department of Dermatology, the third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630

Received:2014-12-02 Online:2015-08-28 Published:2015-08-28

Abstract

Abstract:

Objective The aim of this study was to investigate the epidemiology of pathogenic fungi of onychomycosis in China.Methods Fungal culture and clinical analysis were performed on 1 428 cases of onychomycosis using positive direct microscopic examination.Results Eight hundred strains were isolated, the positive rate was 53.9%.The most frequently isolated fungi were dermatophytes (84%), Trichophyton rubrum accounted for 80.9%, followed by Trichophyton interdigitale and Epidermophyton floccosum. The second was yeasts (11.4%), Candida accounted for 10.1%, mainly included C.parapsilosis, C.albicans and C.tropicalis.Non-dermatophytic moulds accounted for 4.6%, included Acremonium, Aspergillus, Penicillium, Chaetomium, Fusarium and Scopulariopsis.Conclusion In China, the most frequently pathogenic fungi of onychomycosis were dermatophytes, followed by yeasts and non-dermatophytic moulds.

Key words: onychomycosis, pathogenic fungi, multicenter, epidemiological survey

CLC Number:

R756.4

WANG Ai-ping, YU Jin, WAN Zhe, LI Fu-qiu, ZENG Jing-si, LIU Wei-da, ZHANG Qiang-qing, HAO Fei, RAN Yu-ping, XI Li-yan, LAI Wei, LI Ruo-yu. Multi-center epidemiological survey of pathogenic fungi of onychomycosis in China[J]. Chinese Journal of Mycology, 2015, 10(4): 197-202.

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Multi-center epidemiological survey of pathogenic fungi of onychomycosis in China

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