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Chinese Journal of Mycology 2014, Vol. 9  Issue (6): 364-367,363.

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Advances in research on FKS mutation and echinocandin resistance of Candida glabrata

GAO Ying, SHE Xiao-dong, LIU Wei-da   

  1. Department of Mycology, Institute of Dermatology, Chinese Academy of Medical Science&Peking Union Medical College, Nanjing 210042, China
  • Received:2014-06-27 Online:2014-12-28 Published:2014-12-28

Abstract: The proportion of systemic fungal infections in humans caused by C.glabrata has increased significantly in recent years, and in the same time, cases about echinocandins therapeutic failure to this pathogen has been reported more and more.FKS mutation has a significant role in the growth of MIC values and echinocandin resistance, and a lot of elements can effect it.

Key words: Candida glabrata, Fks mutation, MIC, echinocandins resistance

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