[1] Gullo FP, Rossi SA, Sardi Jde C,, et al. Cryptococcosis: epidemiology, fungal resistance, and new alternatives for treatment [J]. Eur J Clin Microbiol Infect Dis, 2013,32(11): 1377-1391.
[2] Park BJ, Wannemuehler KA, Marston BJ, et al. Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS [J]. Aids,2009,23(4):525-530.
[3] Charlier C, Chretien F, Baudrimont M, et al. Capsule structure changes associated with Cryptococcus neoformans crossing of the blood-brain barrier [J]. Am J Pathol,2005,166(2):421-432.
[4] Chang YC, Stins MF, McCaffery MJ, et al. Cryptococcal yeast cells invade the central nervous system via transcellular penetration of the blood-brain barrier [J]. Infect Immun,2004,72(9):4985-4995.
[5] Chen SH, Stins MF, Huang SH, et al.Cryptococcus neoformans induces alterations in the cytoskeleton of human brain microvascular endothelial cells [J]. J Med Microbiol,2003,52(Pt 11):961-970.
[6] Sabiiti W, May RC. Capsule independent uptake of the fungal pathogen Cryptococcus neoformans into brain microvascular endothelial cells [J]. PloS one,2012,7(4):e35455.
[7] Shi M, Li SS, Zheng C, et al. Real-time imaging of trapping and urease-dependent transmigration of Cryptococcus neoformans in mouse brain [J]. J Clin Invest, 2010,120(5):1683-1693.
[8] Olszewski MA, Noverr MC, Chen GH, et al. Urease expression by Cryptococcus neoformans promotes microvascular sequestration, thereby enhancing central nervous system invasion [J]. Am J Pathol, 2004,164(5):1761-1771.
[9] Santangelo R, Zoellner H, Sorrell T, et al. Role of extracellular phospholipases and mononuclear phagocytes in dissemination of cryptococcosis in a murine model [J]. Infect Immun, 2004,72(4):2229-2239.
[10] Noverr MC, Williamson PR, Fajardo RS, et al. CNLAC1 is required for extrapulmonary dissemination of Cryptococcus neoformans but not pulmonary persistence [J]. Infect Immun, 2004,72(3):1693-1699.
[11] Nielsen K, Cox GM, Litvintseva AP, et al.Cryptococcus neoformans {alpha} strains preferentially disseminate to the central nervous system during coinfection [J]. Infect Immun,2005,73(8):4922-4933.
[12] Kim KS. Mechanisms of microbial traversal of the blood-brain barrier [J]. Nat Rev Microbiol, 2008,6(8):625-634.
[13] Charlier C, Nielsen K, Daou S, et al. Evidence of a role for monocytes in dissemination and brain invasion by Cryptococcus neoformans [J]. Infect Immun, 2009,77(1):120-127.
[14] Stie J, Bruni G, Fox D. Surface-associated plasminogen binding of Cryptococcus neoformans promotes extracellular matrix invasion [J]. PloS one,2009,4(6):e5780.
[15] Stie J, Fox D. Blood-brain barrier invasion by Cryptococcus neoformans is enhanced by functional interactions with plasmin [J]. Microbiology,2012,158(Pt 1):240-258.
[16] Chang YC, Jong A, Huang S, et al. CPS1, a homolog of the Streptococcus pneumoniae type 3 polysaccharide synthase gene, is important for the pathobiology of Cryptococcus neoformans [J]. Infect Immun,2006,74(7):3930-3938.
[17] Jong A, Wu CH, Chen HM, et al. Identification and characterization of CPS1 as a hyaluronic acid synthase contributing to the pathogenesis of Cryptococcus neoformans infection [J]. Eukaryot Cell,2007,6(8):1486-1496.
[18] Jong A, Wu CH, Shackleford GM, et al. Involvement of human CD44 during Cryptococcus neoformans infection of brain microvascular endothelial cells [J]. Cell Microbil, 2008,10(6):1313-1326.
[19] Long M, Huang SH, Wu CH, et al. Lipid raft/caveolae signaling is required for Cryptococcus neoformans invasion into human brain microvascular endothelial cells [J]. J Biomed Sci,2012,19:19.
[20] Huang SH, Long M, Wu CH, et al. Invasion of Cryptococcus neoformans into human brain microvascular endothelial cells is mediated through the lipid rafts-endocytic pathway via the dual specificity tyrosine phosphorylation-regulated kinase 3 (DYRK3) [J]. J Biol Chem, 2011,286(40):34761-34769.
[21] Jong A, Wu CH, Prasadarao NV, et al. Invasion of Cryptococcus neoformans into human brain microvascular endothelial cells requires protein kinase C-alpha activation [J]. Cell Microbiol,2008,10(9):1854-1865.
[22] Maruvada R, Zhu L, Pearce D, et al.Cryptococcus neoformans phospholipase B1 activates host cell Rac1 for traversal across the blood-brain barrier [J]. Cell Microbiol,2012,14(10):1544-1553.
[23] Kim JC, Crary B, Chang YC, et al.Cryptococcus neoformans activates RhoGTPase proteins followed by protein kinase C, focal adhesion kinase, and ezrin to promote traversal across the blood-brain barrier [J]. J Biol Chem,2012,287(43):36147-36157.
[24] Huang SH, Wu CH, Chang YC, et al.Cryptococcus neoformans-derived microvesicles enhance the pathogenesis of fungal brain infection [J]. PloS one,2012,7(11):e48570.
[25] Liu TB, Kim JC, Wang Y, et al. Brain inositol is a novel stimulator for promoting cryptococcus penetration of the blood-brain barrier [J]. PLoS Pathog,2013,9(4):e1003247.
|