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Chinese Journal of Mycology 2014, Vol. 9  Issue (3): 182-185.

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Advances in Neurotropism of Cryptococcus neoformans

FA Zhen-Zong, FANG Wei, GU Ju-Lin, LIAO Wan-Qing   

  1. Department of dermatology, Changzheng Hospital, Institute of dermatology and medical mycology, Changzheng Hospital, Key laboratory of molecular medical mycology, PLA key laboratory of medical mycology, Shanghai 200003
  • Received:2014-03-06 Online:2014-06-28 Published:2014-06-28

Abstract:

Cryptococcus neoformans is a kind of opportunistic fungal pathogen which has a predilection for the central nervous system, resulting in devastating meningoencephalitis. In recent years,the study of the mechanism of Neurotropism of Cryptococcus neoformans has made a great progress. Many violence factors of this pathogen and several signing pathways of the host involved in this process have been discovered.

Key words: Cryptococcus neoformans, central nervous system infections, host-pathogen interactions, virulence factors

CLC Number: