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Chinese Journal of Mycology 2014, Vol. 9  Issue (2): 114-118.

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Recent progress of polyamines in microorganisms

YAO Xiang-wen, ZHOU Mi, CAO Ying-ying, JIANG Yuan-ying   

  1. New Drug R&D Center, School of Pharmacy, Second Military Medical University, Shanghai 200433, China
  • Received:2013-08-09 Online:2014-04-28 Published:2014-04-28

Abstract:

Polyamines including putrescine, spermidine, spermine and cadaverine are polycationic molecules with hydrocarbon backbone and multiple amino groups. These subjects are essential metabolites presented in microorganisms. And polyamines involve many physiological processes of microbe, from growth to development and differentiation. Some studies found that polyamines could promote microbial cell proliferation, keep cell membrane, DNA and RNA stable, and play an important role in physiological stress, of late. This review focuses on the metabolism, transport and physiological functions of polyamines in microorganisms to provide more useful information.

Key words: polyamines, microorganisms, metabolism

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