Advances in antifungal effect of sertraline

Abstract

Abstract: The incidence of fungal infections is rising worldwide. Along with the widespread use of antifungal agents, drug resistance is becoming more prominent. However, effective and safe antifungal agents are very scarce in clinics. Therefore, looking for new antifungal agents is a hot focus of researching works at present. Sertraline is a selective 5-serotonin reuptake inhibitors, commonly used in depression, obsessive-compulsive disorder, premenstrual syndrome, and so on. Ten years ago, a few of scholars found that sertraline has a certain inhibitory effect on the vitality of Candida and Aspergillus, and carried on the preliminary discussion about the antifungal mechanism. According to collecting and reading literature at home and abroad, this paper summarize the antifungal effects of sertraline.

Key words: sertraline, fungus, antifungal agents

CLC Number:

R978.5

CAO Wen-juan, LUO Zhi-cheng. Advances in antifungal effect of sertraline[J]. Chinese Journal of Mycology, 2013, 8(6): 378-380,384.

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