Research progress of host’s immune mechanism to resist Aspergillus infection

Abstract

Abstract: With the wide use of broad-spectrum antibiotics, corticosteroids and immunosuppressive drugs, and the rising incidence of AIDS, diabetes etc, the number of immunocompromised patient is increasing. Follow this, invasive Aspergillus infections are increasing gradually and more attentive than before. To clarify the pathogenesis and find the effective treatment of Aspergillus infections are the common propositions for basic researches and clinical workers. Host's immunity plays an important role in the pathogenesis of Aspergillus infection.To master host's immune mechanisms of Aspergillus is the foundation of studying Aspergillus infection. In our article, progresses on the study of host's immune mechanisms against Aspergillus infections are reviewed.

Key words: Aspergillus, invasive aspergillosis, immune mechanism, fungus

CLC Number:

R379.6

YAN Yu-yan, ZHAO Zuo-tao, LIU Hong-gang. Research progress of host’s immune mechanism to resist Aspergillus infection[J]. Chinese Journal of Mycology, 2013, 8(5): 302-306.

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