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Chinese Journal of Mycology 2013, Vol. 8  Issue (4): 241-245.

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Key virulence factors of Aspergillus fumigatus:an update

JIA Zhen-yu, LI De-dong, JIANG Yuan-ying, WANG Yan   

  1. Second Military Medical University, Shanghai 200433
  • Received:2013-06-06 Online:2013-08-28 Published:2013-08-28

Abstract: The pathogenicity of Aspergillus fumigatus is due to its virulence factors. In recent years, some cell surface proteins (e.g. GPI-anchored protein) and toxins (e.g. gliotoxin) are regarded as the key virulence factors of A.fumigatus. In this article, we reviewed the key virulence factors of A.fumigatus and presented the prospect of future studies.

Key words: Aspergillus fumigatus, virulence factor, cell wall, secondary metabolite

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