In vitro activity of Extracts of Juglans against Candida albicans biofilms

Abstract

Abstract: Objective To investigate in vitro effects of Extracts of Juglans on C.albicans biofilms.Methods XTT reduction assay was performed to determine the effect of Extracts of Juglans on C.albicans biofilms and its adherence. The effect of Extracts of Juglans on morphogenesis of C.albicans biofilms was observed by inverted microscopy.Results SMIC₅₀, SMIC₉₀ of Extracts of Juglans against C.albicans biofilms was15.2 μg/mL, 23.4 μg/mL, respectively. Extracts of Juglans at the concentration of >20 μg/mL could inhibit the adherence of C.albicans.Extracts of Juglans at t he concentration of 30 μg/mL could inhibit biofilm formation totally.Conclusions Extracts of Juglans shows potential activity ag ainst C.albicans biofilm in the study.

Key words: Extracts of Juglans, C.albicans, biofilm

CLC Number:

R379.4

YU Xiao-li, WEN Ping, WANG Jun. In vitro activity of Extracts of Juglans against Candida albicans biofilms[J]. Chinese Journal of Mycology, 2013, 8(4): 202-204.

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In vitro activity of Extracts of Juglans against Candida albicans biofilms

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