Research progress of antifungal compound from nature product

Abstract

Abstract: In recent years,the morbidity and mortality rates of infected patients are still increasing.However, the kind of available antifungal drugs are numbered, and the phenomenon of drug resistance made the current station worse. Develop new kindof antifungal drugs become necessary,finding new high-efficient compound with antifungal activity from nature product has been a hot area of research for several years.Expanding alternative therapeutic agents in the treatment of fungal infection and reducing the occurrence of drug resistance might be achieved by screening new chemical entities with antifungal activities from natural products. In order to clarify their antifungal mechanisms, this paper summarized the antifungal agents which have been reported, based on their different chemical structure and origin. This help to develop high efficient new antifungal precursor structure and find the new antifungal targets.

Key words: antifungal, natural compounds, origin

CLC Number:

R978.5

YAN Wu-yan, CAO Ying-ying, JIANG Yuan-ying. Research progress of antifungal compound from nature product[J]. Chinese Journal of Mycology, 2013, 8(2): 111-115.

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