Combination of antifungal therapy

Abstract

Abstract: Nowadays, morbidity and mortality of invasive fungal infection are increasing, especially among immunocompromised patients. However,the range of choices of existing antifungal drugs, most of which have drug toxicities and drug resistance, are limited.The combination use of antifungal drugs which has gradually applied to the clinic provides a new approach for the resistant strains infection and severe fungal infection. This review is about the effects and mechanisms of the combination therapy of different antifungal drugs.

Key words: antifungal drugs, combination therapy, synergistic effect

CLC Number:

R978.5

WEI Bing, LIU Jin-yan, XIANG Ming-jie. Combination of antifungal therapy[J]. Chinese Journal of Mycology, 2013, 8(1): 61-64.

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