Glucocorticoids and invasive fungal infections:a review

Abstract

Abstract:

It is well-known that hyperglucocorticoids play an important role in inducing the fungal infection,especially opportunistic fungal infection,which is attributed to the complex dysregulation of immunity caused by glucocorticoids.The patients, both those with endogenous Cushing's syndrome and, those receiving exogenous glucocorticoid therapy, are especially at risk of invasive fungal infections. A better knowledge of the interplay between glucocorticoid-induced immunosuppression and invasive fungal infections should assist in earlier recognition and establishment of specific prevention and treatment strategies in order to improve outcomes of such infections.

Key words: glucocorticoids, invasive fungal infection, opportunistic infection

CLC Number:

R 756.6

HAO Fei, WANG Li, ZHOU Cun-jian. Glucocorticoids and invasive fungal infections:a review[J]. Chinese Journal of Mycology, 2012, 7(6): 367-371.

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