Biofilm gene expression and biofilm-related genes of Candida albicans:an update

Abstract

Abstract: Candida albicans is an opportunistic fungal pathogen with the ability to form biofilms on in-planted medical devices. Cells in biofilms display a phenotype that is markedly different from their planktonic and free-living counterparts in both form and function.Recent advances in microarray and genetic manipulation have begun to clarify the mechanisms that govern C.albicans biofilm development and acquisition of such unique phenotype. These studies are considered to be important in finding new targets of antifungal drugs.

Key words: Candida albicans, biofilm, gene expression

CLC Number:

R379.4

SHANG Qing-hua, CAO Ying-ying, MIAO Hao, JIANG Yuan-ying. Biofilm gene expression and biofilm-related genes of Candida albicans:an update[J]. Chinese Journal of Mycology, 2012, (2): 125-128.

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